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Aspen based start-up looks to revolutionize health and wellness

Thoryn Stephens, right, wearing a brain cap, and local athlete and coach Ashley Grimmel, who are behind the BRAIN.ONE app, pose on Thursday, Jan. 23, 2025, in front of Aspen Mountain. The app is a brain fitness platform to help develop brain health microhabits and protocols to combat dementia.
Austin Colbert/The Aspen Times

BRAIN.ONE is a revolutionary health and wellness platform that began in Aspen, reshaping how people approach brain fitness and overall well-being. 

By integrating brain and body data through wearable technology, the platform provides biomarker feedback and leverages advanced AI to deliver tailored health protocols. Grounded in science, these protocols help users adjust their micro-habits to optimize both physical and mental health.

The vision for BRAIN.ONE stems from Thoryn Stephens, a Colorado native with a background in molecular and cell biology. 



Stephens started his career as a bench scientist in biotechnology before transitioning into data science. His scientific roots shaped his innovative perspective. 

“Science is very much at my core as a researcher. I was part of the wave of scientists studying genomics, which is the idea of understanding your DNA,” he explained. 




This foundation inspired his fascination with digital measurement. 

“It was from that that I became obsessed with the idea of digital measurement,” he said.

Thoryn Stephens, wearing a brain cap, looks over his app, BRAIN.ONE, on Thursday, Jan. 23, 2025, at Unravel Coffee in Aspen. The app is a brain fitness platform to help develop brain health microhabits and protocols to combat dementia.
Austin Colbert/The Aspen Times

In 2012, Stephens began exploring how social media companies collected and utilized data. While he acknowledged ethical concerns, his primary interest lay in optimizing and measuring data. 

Around the same time, as he trained for his first Ironman, he applied a structured framework involving exercise, nutrition, and measurement to his training. 

“That was the beginning of all of this. The idea that you can use data to manage, or optimize, your biology,” he said. 

For instance, he used heart rate data to regulate his lactic acid threshold, enabling him to fine-tune his performance for aerobic or anaerobic activities.

This concept became the foundation for BRAIN.ONE. The platform enables users to optimize data from wearables like smartwatches to enhance their biology. While athletic training remains a key focus, Stephens emphasized its broader implications. 

“Some studies show that by modifying certain habits, preventative care can be achieved without the need for medication,” he said. “These modifications are often behavioral, targeting risk factors to improve both physical and mental health.”

BRAIN.ONE operates through three interconnected elements: protocols, micro-habits, and feedback loops. 

Protocols provide a structured framework for health management; micro-habits involve actionable steps like cold plunging or yoga; and feedback loops use wearable technology to deliver real-time data. 

“People can follow protocols for health, which could help them stave off disease,” Stephens noted. “This does not require pharmaceuticals and is generally based on behavioral modifications, such as nutrition, movement, and measurements.”

Thoryn Stephens, right, wearing a brain cap, and local athlete and coach Ashley Grimmel, who are behind the BRAIN.ONE app, pose on Thursday, Jan. 23, 2025, in front of Aspen Mountain. The app is a brain fitness platform to help develop brain health microhabits and protocols to combat dementia.
Austin Colbert/The Aspen Times

Launched in Aspen, BRAIN.ONE is offered through a subscription model and is initially targeting practitioners and clinicians. 

The platform has already attracted thousands of additional users on its waitlist, eager to adopt its innovative approach, since the app has not launched outside of its target audience. 

AI technology tailors routines to fit individual needs, creating a highly personalized experience. 

“We all have our daily routines. When you wake up in the morning, what is it that you do? Some people follow very regimented protocols, especially if you are an athlete in training. We have AI that can help optimize that routine based on a particular individual’s inputs,” Stephens explained.

The platform has incorporated insights from professional athletes like former Denver Broncos defensive tackle Malik Jackson and celebrities such as Taylor Swift to refine its data-driven approach. 

Recently, BRAIN.ONE announced a strategic partnership with thought leader Tim Storey, who previously served as Magic Johnson’s sports agent, and Darren Prince, CEO of Prince Marketing Group. Together, Stephens said their expertise and vision are helping propel BRAIN.ONE as a leader in personalized health and wellness.

To learn more, visit BRAIN.ONE.